Abstract

Membrane-bound Klotho is the coreceptor for fibroblast growth factor 23 (FGF23) that increases its affinity for FGF receptors (FGFRs).[1][1] Binding of FGF23 to FGFR-Klotho complexes in the kidney stimulates phosphaturia and inhibits production of 1,25-dihydroxyvitamin D.[2][2] In the parathyroid

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.