Abstract

Genetic investigation of an old infanticide case was conducted using DNA from archival fixed tissues in an attempt to provide independent evidence of the parents identity. The initial PCR assays using DNA extracted from paraffin embedded tissues failed because of possible inhibitors, requiring additional purifying steps. STR profiling was conducted on nine loci plus Amelogenin using PAGE gels. Comparison of the fetal DNA profile with the DNA profiles of the putative mother and her husband revealed the compatibility of the fetal DNA profile with the maternal profile and excluded the man from the paternity.

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