Abstract
Parathyroid hormone (PTH) , a potent anabolic agent, produces larger increments in bone mass than those seen with antiresorptive agents. No further benefit is expected in PTH and antiresorptive combinations in treatment-naïve patients of osteoporosis, but in cases achieving the plateau level of BMD with established alendronate PTH can stimulate bone formation and increase BMD again. Alendronate treatment after PTH therapy can maintain gains in BMD at lumbar spine and hip as well. Many possibilities are expected in the role of PTH therapy in osteoporosis treatment.
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