Abstract
Background: A high worldwide incidence of colorectal cancer defines the importance of search not only for effective treatment methods, but also for risk factors for the cancer development and its worst prognosis. The influence of many genetic factors, environmental characteristics and lifestyle features has already been proven, and recently the attention of researchers is being focused on the study of microbiota and, in particular, various parasitic intestinal diseases in the context of risk factors for colorectal cancer.Clinical case presentation: we demonstrate an incidental finding of parasitic invasion signs during the pathomorphological examination of the surgical specimen in a patient without an epidemiological history.Conclusion: Further studies are needed not only to confirm and substantiate the role of micro- and macroorganisms inhabiting the intestine in the development of oncological diseases, but also to identify individual links of pathogenesis, pathological pathways and signaling molecules involved in carcinogenesis. Research like this could help broaden knowledge about both the risk factors and predictors of colorectal cancer and the potential sites for targeted therapy.
Highlights
A high worldwide incidence of colorectal cancer defines the importance of search for effective treatment methods, and for risk factors for the cancer development and its worst prognosis
Clinical case presentation: we demonstrate an incidental finding of parasitic invasion signs during the pathomorphological examination of the surgical specimen in a patient without an epidemiological history
Общность некоторых звеньев патогенеза и потенциальное влияния хронического воспаления на канцерогенез показывают, что при исследовании факторов риска развития онкологических заболеваний прямой и ободочной кишки необходимо учитывать микробиоту кишечника и паразитарные заболевания как возможных непосредственных участников или триггеров запуска канцерогенных процессов
Summary
A high worldwide incidence of colorectal cancer defines the importance of search for effective treatment methods, and for risk factors for the cancer development and its worst prognosis. Введение В научной литературе встречается описание ряда случаев паразитарных заболеваний кишечника, выявленных случайно при обследовании или лечении пациентов с колоректальным раком [1,2,3]. Однако совместная встречаемость гельминтозов или паразитарных заболеваний и колоректального рака натолкнула многих исследователей на мысль о взаимосвязи этих заболеваний.
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