Abstract

PABA or p-Amino Benzoic Acid is a water-soluble natural vitamin-like compound thought to be important in the synthesis of folic acid. Moreover, PABA has also been implicated in amino acid synthesis, and the biosynthetic pathway of purines and pyrimidine. Interestingly, PABA has been used for a variety of purposes. It is a commonly included in sunscreen lotions do to its ability to absorb UV light. Importantly, PABA has been evaluated in human clinical trials for its efficacy on a number of connective tissue diseases including Dermatomyositis, Peyronie disease and Scleroderma and thus, much of the human pharmacokinetics and toxicities are known.

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