Abstract
A 45-year-old woman received the AstraZeneca vaccine for novel SARS-CoV-2 (COVID-19). Eight days later, she noticed flank pain, blurry vision, severe headaches, and generalized weakness. Computed tomography body scans demonstrated pulmonary embolism and bilateral adrenal hemorrhages. Magnetic resonance imaging/Venography scans of her brain revealed thrombosis of multiple cerebral dural sinuses (Fig A-B, arrows). She was thrombocytopenic and had positive heparin-induced thrombocytopenia assay. Diagnosis of vaccine-induced thrombotic thrombocytopenia (VITT) was made and treatment with intravenous argatroban, immunoglobulins, and hydrocortisone commenced.
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