Abstract

Metastatic pancreatic cancer is rare, accounting for approximately 2% of all pancreatic malignancies, and most cases arise from renal cell carcinoma. We report the case of a 63-year-old woman, who presented with a pancreatic tumor detected during her annual health examination. She had undergone left nephrectomy 13 years previously for renal cell carcinoma. Computed tomography (CT) revealed two tumors in the head and body of the pancreas, a hypervascular tumor and a hypovascular tumor with an enhanced rim, respectively. She underwent pylorus-preserving pancreaticoduodenectomy, and metastatic pancreatic tumors arising from the kidney with clustered clear cell carcinoma immunohistochemically positive for CD10 were diagnosed. This report presents the different enhancement features of different lesions on CT scans. Because the enhancement features of lesions have been reported to vary according to the size of the metastatic tumor, a knowledge of the history of renal cell carcinoma is crucial for diagnosis.

Highlights

  • Isolated metastasis to the pancreas is rare, ranging in incidence from 2% to 5% in clinical studies [1,2,3,4,5,6]

  • We reviewed the radiological features of pancreatic metastases from Renal cell carcinoma (RCC) shown by dynamic Computed tomography (CT) scans (Table 1)

  • We reviewed studies published from 1998 to 2013 that focused on surgical resection of the pancreas for metastases from RCC

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Summary

Introduction

Isolated metastasis to the pancreas is rare, ranging in incidence from 2% to 5% in clinical studies [1,2,3,4,5,6]. Most patients with pancreatic metastases are asymptomatic, whereas some exhibit jaundice or abdominal pain [12]. Of patients with pancreatic metastases, 12% present with synchronous extrapancreatic metastasis, and they have a poor prognosis [13,14]. Surgical treatment for isolated metachronous pancreatic metastases from RCC has been reported in recent years to improve prognosis [6,13,14,15,16,17].

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