Abstract
The palladium-catalysed arylation of free OH phenol derivatives proceeds regioselectively either at C2 or at OH with a variety of electron-deficient aryl bromides or heteroaryl bromides. The nature of the base was found to be crucial to control the regioselectivity of the reaction. In the presence of potassium acetate, the direct arylation at C2 is favoured; whereas, under the same reaction conditions, the use of potassium carbonate gave selectively the O-arylation type products.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
