Abstract
Back pain resulted from spine disorders reaches 60–80% prevalence in humans, which seriously influences life quality and retards economic production. Conventional electrical pain relief therapy uses radiofrequency to generate a high temperature of 70–85 °C on the electrode tip to destroy the neural transmission and stop the pain. However, due to the larger area of stimulation, eliciting significant side effects, such as paralysis, contraction, and a slightly uncomfortable feeling, our study aimed to design a tiny and stretchable neural stimulatory electrode that could be precisely anchored adjacent to the dorsal root ganglion which needs therapy and properly interfere with the sensory neural transmission. We also designed a subcutaneously implantable wireless power transmission (WPT) device to drive the neural stimulatory electrode. Through the study, we elaborated the design concept and clinical problems, and achieved: (1) the architecture design and simulation of the transdermal wireless power transferred device, (2) a wrap-able pulsed radiofrequency (PRF) stimulatory electrode, (3) an insulation packaging design of the titanium protection box. The feasibility study and hands-on prototype were also carried out.
Highlights
The neck or back pain resulting from spine disorders, including acute back pain and chronic lower back pain that continues for several months, reaches 60–80% prevalence in humans
We designed a rectangular box with a cortex wire architecture for the wireless energy transmission device, featuring a glass plate as the antenna support and surface packing material
This architecture designed here was different from the patented conventional implantable medical devices and prevented the use of materials with high magnetic conduction coefficients applied in the implantable wireless energy transmission
Summary
The neck or back pain resulting from spine disorders, including acute back pain and chronic lower back pain that continues for several months, reaches 60–80% prevalence in humans. These kinds of pain would not immediately affect human life, they do seriously influence life quality and retard economic production. A population of over 75 million in U.S are suffering from chronic neuron disease-induced pain, and the costs of therapeutics and medical treatments have reached 2.3 billion with a year-on-year (YOY) of 12.1% [5,6]. Pain feeling transmission was impeded to achieve pain relief by the electric field effect released from the implanted PRF neural stimulatory device which stimulated neurons in the transmission pathway. A therapeutic temperature lower than 42 ◦ C of the PRF
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