Abstract

High resolution SFC separations of polysiloxanes using standard bore and 2 mm ID packed columns with pressure and density programming of pure carbon dioxide are demonstrated. Independent control of flow and pressure allowed enhanced resolution, particularly at higher molecular weights, over previous separations. More than 150 individual homologs of dimethylsiloxanes were at least partially resolved, allowing differentiation of molecular weight to over 11,000. Pure carbon dioxide appeared to be capable of eluting molecular weights up to an estimated 25,000.

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