Abstract

Pachymeningeal en plaque tuberculoma is a rare manifestation of tuberculosis and has a poor prognosis if not diagnosed early and treated adequately. The aim of the present paper is to collect the reported clinical and radiological signs in the literature and compare it with a personal observation to evaluate the possibility of a presumptive diagnosis. A 4-year-old boy presented at the pediatric emergency department with 7 days history of severe headache, vomiting blurred vision and had one partial seizure. His neurologic examination was notable for decreased visual acuity with bilateral papilledema and intact extra-ocular muscles. His neck was rigid. Neuroimaging revealed a multifocal dural-based mass on the fronto-parietal convexity with dense heterogeneous contrast enhancement and hydrocephalus. He has undergone a Ventriculoperitoneal shunt and surgical excision of the mass the next day. Outcome was favorable with antituberculosis therapy and corticosteroids. The clinical presentation and outcome were similar to the reported cases in the literature.

Highlights

  • Pachymeningeal en plaque tuberculoma is a rare manifestation of tuberculosis and has a poor prognosis if not diagnosed early and treated adequately

  • Pachymeningeal tuberculoma is a rare localization of neuro-meningeal tuberculosis (TB) secondary to pachymeningitis due to an infection with mycobacterium tuberculosis [1]

  • The aim of the present work was to gather clinical and neuroradiological arguments that could evoke the diagnosis of this particular localization of neuro-meningeal tuberculosis through a review of similar cases reported to date in the literature

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Summary

Introduction

Pachymeningeal tuberculoma is a rare localization of neuro-meningeal tuberculosis (TB) secondary to pachymeningitis due to an infection with mycobacterium tuberculosis [1]. Pachymeningitis has been described as diffuse or localized thickening of the cranial dura mater with or without associated inflammation

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