Abstract

Pachydrusen: the epidemiology of pachydrusen and its relevance to progression of pachychoroid disease spectrum.

Highlights

  • We retrospectively evaluated the clinical case records and multimodal imaging of consecutive patients with pachychoroidopathy with a minimum follow-up duration of one year, who presented to the vitreoretinal services at Giridhar Eye Institute, Kochi, Kerala, India between January 2015 and April 2016

  • On the basis of multimodal imaging, the eyes were categorized into four pachychoroid variants: Pachychoroid pigment epitheliopathy (PPE), Acute /Chronic central serous chorioretinopathy (CSCR), Pachychoroid neovasculopathy (PNV), Polypoidal choroidal vasculopathy (PCV)

  • Progression of PD to PCV (Aneurysmal type 1 CNVM) development was noted in 9/28 eyes (32.14%), that was confirmed by co-localization of color fundus photography (CFP) with multimodal imaging, including OCT, digital fluorescein angiography (DFA) and indocyanine green angiography (ICGA)

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Summary

Introduction

We retrospectively evaluated the clinical case records and multimodal imaging of consecutive patients with pachychoroidopathy with a minimum follow-up duration of one year, who presented to the vitreoretinal services at Giridhar Eye Institute, Kochi, Kerala, India between January 2015 and April 2016. On the basis of multimodal imaging, the eyes were categorized into four pachychoroid variants: Pachychoroid pigment epitheliopathy (PPE), Acute /Chronic central serous chorioretinopathy (CSCR), Pachychoroid neovasculopathy (PNV), Polypoidal choroidal vasculopathy (PCV). Prevalence of PD at baseline was noted and progression to disease activity at its site was analyzed longitudinally by a single masked observer (J.S.).

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