Abstract
While addictive drugs share dopaminergic brain targets, morphological differences between psychostimulant and opiate addiction remain unresolved. Opiate use impacts cue-extinction [via ventromedial prefrontal cortex (vmPFC)] and nucleus accumbens (NAcc) neuroplasticity in rodents, while psychostimulants accompany increased impulsivity [via inferior frontal gyrus (IFG)] in rodents and humans. We hypothesized parallel gray matter volume (GMV) changes in individuals with cocaine or heroin use disorder (CUD/HUD): decreased NAcc/vmPFC GMV in HUD and IFG in CUD.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
