Abstract
P16-35. Specific CD4 responses to HIV-1 epitopes in exposed seronegative (ESN) versus infected commercial sex workers
Highlights
A long standing study of low social economic status commercial sex workers in the Majengo cohort has demonstrated variable susceptibility to HIV-1 infection, where some of the highly exposed subjects remain persistently seronegative signifying resistance to HIV-1
AIDS Vaccine 2009 Anna Laura Ross Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1471-2105-10-S12-info.pdf
Current research has shown that MHC alleles play a significant role in the possible mechanisms of resistance. If both HIV infected and resistant individuals have HIV specific T helper responses, there is a certain uniqueness that protects the latter group from contracting the disease
Summary
Specific CD4 responses to HIV-1 epitopes in exposed seronegative (ESN) versus infected commercial sex workers. Address: 1Immunology, Kenya AIDS Control Project, Nairobi, Kenya and 2University of Manitoba, Winnipeg, Canada * Corresponding author from AIDS Vaccine 2009 Paris, France. Published: 22 October 2009 Retrovirology 2009, 6(Suppl 3):P264 doi:10.1186/1742-4690-6-S3-P264. AIDS Vaccine 2009 Anna Laura Ross Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1471-2105-10-S12-info.pdf
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