P0606OUTCOME OF CANCER PATIENTS WITH ACUTE KIDNEY INJURY REQUIRING DIALYSIS

Abstract

Abstract Background and Aims Recent advances in treatment of cancer lead to improvement in mortality among cancer patients. However, data regarding outcomes of cancer patients with acute kidney injury (AKI) requiring dialysis were scarce. We conducted this study to see the difference in mortality and other outcomes between cancer and non-cancer patients who had AKI requiring dialysis. Method We reviewed medical record of previous 18 months in our institute. Patients with age at least 18 years with acute kidney injury requiring dialysis were included in our study. Primary outcome was mortality at 30 days. Renal recovery and chronic kidney disease (CKD) after AKI events were also recorded. Results A total of 61 patients were included in our study; 28 patients had no cancer and 33 patients had cancer. Of cancer patients, 81.8% had advanced stage cancer. Modality of dialysis was continuous renal replacement therapy in 36.1%. Mortality at day 30 was not significantly different between cancer patients and non-cancer patients (57.6% vs. 53.6%, P = 0.754). Of alive patients, renal recovery among cancer patients and non-cancer patients was also not significantly different (69.2% vs. 50.0%, P = 0.310). CKD after episodes of AKI was also not significantly different between cancer patients and non-cancer patients (42.8% vs. 77.8%, P = 0.302). Conclusion This is the first study to compare mortality between cancer and non-cancer patients who had AKI requiring dialysis. We found no significant difference regard to mortality between AKI patients requiring dialysis with and without cancer. Renal recovery and CKD development were also not significantly different between two groups. More studies in nephro-oncology field are required for better treatment in cancer patients.