Abstract
As for PFS, SMI [hazard ratio (HR) (95% CI): 1.041 ((1.003-1.081))], SMD [HR (95% CI): 1.113 (1.035-1.197)], and pre-therapeutic alkaline phosphatase (ALP) [HR (95% CI): 1.003 (1.001-1.005)], and ΔSMD [HR (95% CI): 1.113 (1.035-1.197)] were considered as prognostic predictors with statistical significance (p<0.05). Our results showed patients with lower SMD had prognostic value for prediction of poorer OS compared with patients with higher SMD with HR of 1.113 (95%CI: 1.035-1.197, p=0.004).
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