P 130 Indicators of EEG in epileptic encephalopathy in children

Abstract

Relevance Epilepsy is one of the most urgent problems of paediatric neurology, because of behavioural, mental, neuropsychological impairments, the difficult diagnosis and curable of the disease, especially if there are non-trivial paroxysms. The frequency of childhood epilepsy is on foreign sources of 0.5–0.75% of the child population. International antiepileptic League recently in the classification of epileptic syndromes put term epileptic encephalopathy. Epileptic encephalopathy - a condition in which the epileptiform disturbances lead to progressive disorder of brain function. From a clinical point epileptic encephalopathy divided into 2 types: 1-type - occurs in children with epileptic syndromes, marked by progressive disorders of cognition, intelligence, speech and other cerebral functions. 2-type - is characterized by mental, cognitive, behavioural and social disorders in the absence of seizures. Purpose of the study Explore electroencephalographic features of the epileptic encephalopathy in children. Material and methods We studied 27 children aged 3–14 years who were hospitalized in the paediatric neurology clinic TashPMI, with a sharp mental retardation or gross psychomotor retardation. The study patients were divided into 2 groups. Clinical and neurological examination of children in group I - 15 children revealed diffuse focal neurological symptoms, marked an intellectual deficit. The history of these patients had generalized seizures and polymorphic. The EEG data from children revealed a giant amplitude sharply slow wave and spike wave dysrhythmia, hypsarrhythmia. Clinical and neurological examination of children of group II - 12 children, found no gross localized neurological disorders have been observed hyperactive type of behavior, the backlog in training at the school relative to their peers. In this subgroup of patients did not have a history of epileptic seizures. On the EEG data revealed a high amplitude and a constant stem dysrhythmia sharply slow wave dysrhythmia. In addition, these patients have a family history met “small” signs of epilepsy. Children in both groups were appointed by anticonvulsant drugs. The treatment of children have improved somewhat cognitive function. Conclusion This study demonstrates the importance of neurophysiological research methods for children with retarded mental and psychomotor development in order to eliminate or timely diagnosis and treatment of this disease.