Abstract

Splenectomised patients are more likely to suffer from severe infections, such as sepsis and meningitis. This condition is called overwhelming postsplenectomy infection (OPSI) syndrome. The risk of OPSI is greatest in the early months, and even years, after the operation, but never disappears entirely. The course of OSPI is rapid, the clinical presentations serious, and the prognosis poor. We present here a case of OPSI in a posttraumatic splenectomised adult who had features of fulminant sepsis such as hypotension, renal and liver failure, coagulopathy, and generalised skin rash presented as purpura fulminans. The culprit was found to be Streptococcus suis by the polymerase chain reaction technique. By reporting this case, we hope to emphasize the importance of preventive strategies: vaccination, antibiotic prophylaxis, and patient education. The management of Streptococcus suis infection and the use of 16S rRNA gene sequencing for bacterial identification were also highlighted.

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