Abstract
AbstractIn the disciplines of pharmaceutical chemistry and drug discovery process, thiazole derivatives are one of the most prominent and widely used heterocycles. The distinctive structural features processed by thiazoles place them in the special category of molecules that are essential in biological and medicinal chemistry fields. The thiazole cores exhibit a broad extent of pharmacological and biological activities using weak interactions with receptors and enzymes in the biological system. In particular, several thiazole derivatives with immense therapeutic potency have been well explored as clinical drugs to treat different types of diseases. This chapter illustrates the current developments on thiazole derivatives as antitumour, antimicrobial, anti‐inflammatory, antiviral, anticancer and other medicinal agents to attain prominence in medicinal chemistry fields.KeywordsThiazolesN-heterocyclesDrug DiscoveryKinase InhibitorPharmacokinetics
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