Abstract

Stereotactic body radiation therapy (SBRT) has emerged as the treatment of choice for medically inoperable stage I non-small cell lung cancer (NSCLC). At the same time, distinct genetic sub-groups of NSCLC have been defined by mutations in oncogenes such as K-ras. In this retrospective study, we compare outcomes after lung SBRT in patients (pts) with K-ras mutant (K-ras mut+) NSCLC versus pts with wild-type or unknown K-ras status (K-ras wt/unk).

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