Abstract
ETHACRYNIC acid is a potent new diuretic which causes sodium and potassium excretion. It is especially useful in patients with refractory edema, cardiac decompensation, hepatic cirrhosis, and renal disease. Side effects such as gastrointestinal symptoms, hypoglycemia, and hyperuricemia, are not unusual. A granulocytosis and neutropenia have been reported. Recently Maher and Schreiner, 1 and Schneider and Becker 2 have reported transient hearing loss following the administration of ethacrynic acid in humans. A cysteine derivative of ethacrynic acid was withdrawn from clinical use because of high incidence of transient hearing loss. The purpose of this paper is to report a case of hearing loss and describe the pathology following the administration of ethacrynic acid. Report of a Case The patient was a 53-year-old woman who was hospitalized with hepatic cirrhosis, acute renal failure, and esophageal varices. Examination revealed a severely jaundiced individual with ascites, enlarged liver and spleen. Shortly after admission
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Archives of Otolaryngology - Head and Neck Surgery
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
