Abstract
Osteosarcoma of jaw is a rare malignant condition of osteoid tissue with same histopathological features but different biological behaviour compared to long bone. It has characteristic clinical, radiographic and histopathologic features and treatment after early diagnosis followed by surgery (with negative margin) combined with chemotherapy or radiotherapy has better prognosis and survival rate. Here we report the case of osteosarcoma of mandible after tooth extraction in a 55-year-old female and treated by surgery
Highlights
Osteosarcoma is an aggressive, most common malignant neoplasm of mesenchymal origin characterized by the formation of osteoid tissue by sarcomatous stroma.[1,2]
The overall survival rate is 40-50% and the better prognosis depended upon early diagnosis, wide excision with negative surgical margin and a low grade tumor.[11] apparently well 5 months ago she experienced toothache on right side of lower jaw for which she had extraction of 1st molar by local dentist
Osteoid formation by malignant cells along with areas of mitosis and myxoid at places were seen. These histological features were suggestive of osteosarcoma of the mandible
Summary
Osteosarcoma is an aggressive, most common malignant neoplasm of mesenchymal origin characterized by the formation of osteoid tissue by sarcomatous stroma.[1,2] It mainly affects long bone and is rare in jaw (about 5% to13%) with more mandibular involvement than in maxilla.[3]. The overall survival rate is 40-50% and the better prognosis depended upon early diagnosis, wide excision with negative surgical margin and a low grade tumor.[11] apparently well 5 months ago she experienced toothache on right side of lower jaw for which she had extraction of 1st molar by local dentist. The dental history revealed extraction of right 1st molar 5 month ago. According to patient, she was Figure 1: Picture showing intraoral view of osteosarcoma. After proper counselling and taking informed written consent resection of tumour from right side of body to the left side of body of mandible distal to left first molar with 1.5 cm of clinical healthy margin (Figure 4). The prognosis and outcome of the patient was good with period of disease free survival till date and reduced symptoms and functional debility with 3 monthly follow up
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
