Abstract
This study aimed to describe 21 cases of osteoradionecrosis (ORN) in patients undergoing radiotherapy in the head and neck region. ORN cases diagnosed between January 2010 and December 2020 in a southern Brazil hospital were selected. ORN demographic data and clinical features were collected. Men (n=16/76.2%) with a mean age of 60.9 (34.5; 70.9) years were more affected. The tumor's primary sites were the mouth (n=12), oropharynx (n=7), hypopharynx (n=1), and skin (n=1), with Squamous Cell Carcinoma (n=19), Cystic Adenoid Carcinoma (n=1), and Adenocarcinoma (n=1) diagnoses. The mandible was the most affected location (n=19/90.48%), with an average time of ORN development of 60.9 (2.1; 80.3) months after radiotherapy treatment. In 13 (61.9%) patients, post-radiotherapy tooth extractions were performed and were considered the triggering factor. ORN is more common in the mandible of male patients undergoing tooth extraction after radiotherapy. Dental evaluation prior to radiotherapy treatment is necessary to minimize ORN development. This study aimed to describe 21 cases of osteoradionecrosis (ORN) in patients undergoing radiotherapy in the head and neck region. ORN cases diagnosed between January 2010 and December 2020 in a southern Brazil hospital were selected. ORN demographic data and clinical features were collected. Men (n=16/76.2%) with a mean age of 60.9 (34.5; 70.9) years were more affected. The tumor's primary sites were the mouth (n=12), oropharynx (n=7), hypopharynx (n=1), and skin (n=1), with Squamous Cell Carcinoma (n=19), Cystic Adenoid Carcinoma (n=1), and Adenocarcinoma (n=1) diagnoses. The mandible was the most affected location (n=19/90.48%), with an average time of ORN development of 60.9 (2.1; 80.3) months after radiotherapy treatment. In 13 (61.9%) patients, post-radiotherapy tooth extractions were performed and were considered the triggering factor. ORN is more common in the mandible of male patients undergoing tooth extraction after radiotherapy. Dental evaluation prior to radiotherapy treatment is necessary to minimize ORN development.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.