Abstract
Due to limited available information on the occurrence and treatment of uterine cancer, health institutions in major countries trend to study some factors and diseases that may relation or plays as predisposing factors of the occurrence of uterine cancer and the lack of previous studies on the impact of osteoporosis on the incidence of uterine cancer and the rapid spread of uterine cancer in recent years all over the world and till know the exact mechanism is not fully clear. This study focused on the following: possibility of osteoporosis as a marker of uterine cancer by studying the relationship between osteoporosis and uterine cancer through a biochemical and hormonal parameters responsible for osteoporosis and its effect on uterus and possibility of malignant changes. The study included collection of samples attending the Hospitals in Mosul, from 82 women had no uterine cancer and divided to two groups (44 healthy women and 38 women diagnosed as osteoporosis only) and 101 women with uterine cancer (43 with uterine cancer only and 58 women are associated osteoporosis with uterine cancer dose not received any treatment for their condition). Each patient was evaluated clinically and by a biochemical laboratory tests, which include phosphorus, calcium, vitamin D3, alkaline phosphatase ALP, estrogen and progesterone in serum by using commercial kits. The results showed the osteoporosis may increases the incidence of uterine cancer. Novel of this research showed that Osteoporosis is a new risk factor for uterine cancer. Accordingly, women should pay attention for her bone health and early diagnosis and treatment of osteoporosis to prevent and reduce the risk of uterine cancer.
Highlights
Uterine cancer is the third most common malignant tumors in women and the incidence of uterine cancer has doubled over the last six years
The study included collection of samples attending the Hospitals in Mosul, from 82 women had no uterine cancer and divided to two groups (44 healthy women and 38 women diagnosed as osteoporosis only) and 101 women with uterine cancer (43 with uterine cancer only and 58 women are associated osteoporosis with uterine cancer dose not received any treatment for their condition)
The results showed the osteoporosis may increases the incidence of uterine cancer
Summary
Uterine cancer is the third most common malignant tumors in women and the incidence of uterine cancer has doubled over the last six years. Where more than 40% of malignant tumors in women is a cancer of the uterus. Osteoporosis is common in older people and in postmenopausal women It is a growing health problem worldwide and women in pre-menopausal stage are at high risk the disease after the twenty years. There is need for further studies to verify that the protective effect of calcium and vitamin D can be expanded to uterine cancer (Byers, 2010). Mahfoth Al-noaymy / American Journal of Applied Sciences 11 (1): 105-108, 2014 by studying the relationship between osteoporosis and uterine cancer through a biochemical and hormonal parameters responsible for osteoporosis and its effect on uterus and possibility of malignant changes and this is done for the first time
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