Abstract
First described in 1904, Osteopetrosis (OP) is a rare genetic disorder [1] affecting osteoclast activity resulting in decreased bone resorption and bone densification [2]. There are three types of osteopetrosis depending on the world of transmission: autosomal dominant OP, autosomal recessive OP, and intermediate autosomal OP [3]. Indeed, osteopetrosis is characterized by a hard but fragile bone with a narrow or absent medullary canal [4]. Consequently, the bone is so dense and fragile that it is subject to an increased risk of fractures and complications during surgery, which is why patients with OP are treated conservatively [5]. Furthermore, due to poor blood supply, patients with osteopetrosis have a high risk of infection and osteomyelitis, in addition to the risk of pseudarthrosis [6].
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