Abstract
Osteoma cutis is a benign cutaneous lesion characterized by the presence of bone within the dermis or subcutaneous fat. It most often develops in association with other skin lesions such as cutaneous tumors. Nevus sebaceus is a benign hamartoma of the skin that is composed of epidermal and dermal components. It most commonly appears on the scalp and may give rise to either benign or malignant secondary neoplasms. The clinical and pathologic features of a 36-year-old man with a nevus sebaceus and associated osteoma cutis are described. In addition, osteoma cutis-associated neoplasms are reviewed. Secondary osteoma cutis has been observed with both benign and malignant neoplasms as well as various non-neoplastic skin conditions. However, to the best of our knowledge, osteoma cutis has not previously been described in association with nevus sebaceus. Nevus sebaceus can now be added to the list of cutaneous osteoma-associated skin tumors (COASTs).
Highlights
Osteoma cutis, the heterotropic deposition of bone within the dermis, may either present rarely as a primary skin lesion or more commonly secondary to another cutaneous condition
Nevus sebaceus is a benign hamartoma of the skin that is composed of epidermal and dermal components
Osteoma cutis can be added to the conditions associated with nevus sebaceus and nevus sebaceus can be added to the list of cutaneous osteoma-associated skin tumors (COASTs)
Summary
The heterotropic deposition of bone within the dermis, may either present rarely as a primary skin lesion or more commonly secondary to another cutaneous condition. Distant (a) and closer (b) views of secondary osteoma cutis associated with nevus sebaceus on the central scalp of a 36-year-old Filipino man. Microscopic examination demonstrated hyperkeratosis, papillomatosis, and acanthosis with an increased number of sebaceous and apocrine glands in the dermis These findings established a diagnosis of nevus sebaceus (Figure 2). Distant (a) and closer (b and c) magnification views of secondary osteoma cutis associated with nevus sebaceus. There are an increased number of apocrine glands (blue arrows) and enlarged sebaceus glands (SG); in addition, osteoma cutis (black arrow pointing at bone) is present. Correlation of the clinical presentation and pathologic findings established a diagnosis of nevus sebaceus associated with secondary osteoma cutis.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
