Abstract

Odontogenic fibroma (OF) is a rare benign odontogenic neoplasm that is most commonly found in the mandibular/premolar region of female patients in the second to fourth decades of life. Well-defined radiolucent lesions that may induce root resorption are normally observed. Rare variants of OF have been described in the prior literature, including references to: 1) giant cell lesions, 2) amyloid-like protein deposition, and 3) ossifying variants. Immunohistochemistry can contribute to understanding the biological behavior and the pathogenesis of OF. Therefore, this case report aimed to describe a new case of ossifying OF and discuss the histopathology and immunohistochemical features. Key words:Odontogenic fibroma, jaw tumors, ossifying variant.

Highlights

  • Odontogenic fibroma (OF) is a rare benign odontogenic neoplasm

  • The cytokeratin (CK) expression may well be a useful tool to confirm the diagnosis of OF in epithelium-poor cases and to reveal the main types expressed in the OF when compared to other odontogenic tumors [3]

  • The present study is aimed to describe a rare case of ossifying odontogenic fibroma and discuss the histopathology and immunohistochemical features of this rare variant of OF

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Summary

Ossifying odontogenic fibroma

Márcio-Bruno-Figueiredo Amaral 1, Giovanna-Ribeiro Souto 1, Martinho-Campolina-Rebello Horta 2, RicardoSantiago Gomez 1, Ricardo-Alves Mesquita 1. Ossifying odontogenic fibroma: A rare case report.

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