Abstract
Summary. Exposure of normal red cells to lead in vitro is known to result in decreased osmotic fragility. Red cells from a normal individual and from two children with genetically determined red‐cell abnormalities (spherocytosis and elliptospherocytosis) were exposed to lead acetate solution. Osmotic fragility curves were determined for treated and untreated red cells. Exposure to lead was found to increase the osmotic resistance of normal as well as abnormal red cells.
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