Abstract

Background:Coeliac disease is a chronic enteropathy that remains a challenge for the clinician, due to its atypical manifestations and etiopathogenic complexity.Objective:This article intends to describe the oral characteristics of Coeliac Disease in children in order to facilitate their management in the dental office.Methods:A review of the literature was performed electronically in PubMed (PubMed Central, and MEDLINE) for articles published in English from 2000 to April of 2017. The article is also based on the authors' clinical experience with children with coeliac disease. The searched keywords were “coeliac disease “,”oral manifestations “, “dental enamel defects”, “recurrent aphthous stomatitis” and “oral aphthous ulcers”.Results:There are some oral manifestations which are strictly related to coeliac disease: dental enamel defects, recurrent aphthous stomatitis, delayed tooth eruption, multiple caries, angular cheilitis, atrophic glossitis, dry mouth and burning tongue.Conclusion:The complete knowledge of the oral manifestations of coeliac disease can trigger an effective change in the quality of life of the patients with this disease.

Highlights

  • Coeliac disease (CD) is an immune-mediated enteropathy that affects genetically susceptible subjects following exposure to gluten in the diet [1 - 3]

  • There are some oral manifestations which are strictly related to coeliac disease: dental enamel defects, recurrent aphthous stomatitis, delayed tooth eruption, multiple caries, angular cheilitis, atrophic glossitis, dry mouth and burning tongue

  • The complete knowledge of the oral manifestations of coeliac disease can trigger an effective change in the quality of life of the patients with this disease

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Summary

Introduction

Coeliac disease (CD) is an immune-mediated enteropathy that affects genetically susceptible subjects following exposure to gluten in the diet [1 - 3]. In different parts of the world the prevalence of CD has been estimated to be approximately 0.5%-1% [4, 7] Current research in this area enables the detection of silent forms of the disease and makes it possible to assess its real prevalence, which is higher than initially thought [2]. This disorder is characterized by typical histological jejunal lesions showing total or subtotal villous atrophy, crypt hyperplasia and lymphocyte infiltration, which results in malabsorption of most nutrients in the small intestine [8, 9]. Coeliac disease is a chronic enteropathy that remains a challenge for the clinician, due to its atypical manifestations and etiopathogenic complexity

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Conclusion

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