Oral administration of baker’s yeast (Saccharomyces cerevisiae) acts as a growth promoter and immunomodulator in Labeo rohita (Ham.)

Abstract

The effect of baker’s yeast ( Saccharomyces cerevisiae ), in the diet of the Rohu ( Labeo rohita ) innate immune response were investigated. Indian major carps Labeo rohita were fed with four different diets for eight weeks: a formulated diet as control diet and the same diets supplemented with 5%, 7.5% and 10% baker’s yeast as an experimental diets. After every fifteen days interval different growth parameters ( such as ADG, SGR, FCR and PER), Serological parameters ( such as TSP,TSA, TSG and A:G), different Hematological parameters ( such as TLC,TEC, Hct, MCV and MCH ) and different Non- specific immunological parameters ( such as PR, PI, Respiratory Burst activity) were evaluated during experimental trial. At the end of the experimental period, fishes of all the tanks were challenged with pathogenic bacteria Aeromonas hydrophila . The results show that, yeast cell wall able to enhance the innate immunity and also have a positive co-relation with growth parameters. Through the absorption of yeast wall particle, the immune function and disease resistance of the entire organism is stimulated. These results support the possible use of baker’s yeast as natural immunostimulants in common fish diets.