Abstract
The defibrillation process is simulated using a wide spectrum of spatial models [1]. It is difficult to use most spatial models to simulate and select the optimal bipolar electric defibrillation pulse. In practice, simpler spatial models are used [2, 3]. In this work, bipolar pulses of external defibrillators were optimized based on the repolarization hypothesis. The algorithm of the optimization is based on a simple model of defibrillation pulse effect on myocardium cell membrane (Fig. 1) [2, 3]. The defibrillation pulse is applied to resistor Rs (the patient’s chest resistance). The signal from resistor Rs is applied to the model of myocardium cell membrane response to an external effector. This model consists of serially connected resistor Rm (cell membrane resistance) and capacitor Cm (cell membrane capacitance). The time constant of cell mem brane reaction to the defibrillation pulse τm is a quantita tive parameter of the myocardium cell reaction to the defibrillation pulse:
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