Abstract

We describe a four-layered model for near infrared light propagation in a human head based on the Monte Carlo method. With the use of three-dimensional voxel-based media discretization, photon migration in the brain is analyzed by both the time-of-∞ight measurement and the spatial sensitivity proflle. In the measurement of brain activity, the selection of light wavelength and the distance between the source and the detector have a great in∞uence on the detected signal. In this study, we compare the detected signals from the detectors with difierent source-detector spacing at wavelengths of 690nm, 800nm and 1300nm, and flnd that in our model, the wavelength of 1300nm is more appropriate for the measurement of brain activity because the signals at 1300nm get better detection sensitivity and spatial resolution. Source-detector spacing is also optimized.

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