Abstract
Sickle cell retinopathy is caused by retinal ischemia secondary to the sickling of red blood cells in retinal arterioles, which supply nutrients to the ganglion cell layer, inner nuclear layer, and Muellerian glia of the retina. Macular infarction due to sickle cell disease has been documented using fluorescein angiography, electroretinography, and histopathologic examination. 1–3 However, optical coherence tomography (OCT) of sickle cell retinopathy has, to our knowledge, never previously been reported. We report a case of macular atrophy secondary to retinal arteriolar occlusion in a patient with sickle cell disease, documented by standardresolution OCT and ultrahigh-resolution OCT, a new imaging technology capable of 2- to 3μm resolution in the axial direction 4 compared with 10 μm with standard-resolution OCT. 5
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