Abstract
The signal of magnetic resonance imaging (MRI) can be enhanced by several orders of magnitude using hyperpolarization. In comparison to a broadly used dynamic nuclear polarization (DNP) technique that is already used in clinical trials, the parahydrogen (H-based hyperpolarization approaches are less cost-intensive, are scalable, and offer high throughput. However, a H generator is necessary. Available commercial H generators are relatively expensive (EUR 10 000-150 000). To facilitate the spread of H-based hyperpolarization studies, here we provide the blueprints and 3D models as open-source for a low-cost (EUR ) 50-bar liquid-nitrogen-cooled H generator.
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