OP-071 THE ASSOCIATION BETWEEN CORONARY ARTERY ECTASIA AND NEUTROPHIL/LYMPHOCYTE RATIO

Abstract

and severity of coronary artery disease indicated by Gensini score in middle-aged Turkish men. Methods: Between October 2011 and April 2012, 124 middle aged (40–59) male patients with known or suspected coronary artery disease were included in the study. Coronary angiography was performed in all patients and Gensini score was calculated. Total serum testosterone levels were measured. The relation between serum testosterone levels and Gensini score was studied. Results: The mean age of the patients was 51.76±5.47. The mean Gensini score of the patients was 44.11±39.08. The mean plasma T level was 3.51±1.39ng/ml. There was no correlation between T levels (r = 0.236, p > 0.05) and HDL-C levels (r = 0.081, p > 0.05) and TG levels (r = −0.044, p > 0.05). There was a correlation between serum T levels and TC levels (r = 0.236, p: 0.008), LDL-C levels (r = −0.210, p: 0.019), and body surface area (BSA) (r = −0.286, p: 0.001). When the patients with coronary artery disease (Gensini score ≥1) were compared with control group (n =29, Gensini score: 0), the mean serum testosterone levels were lower (3.37±1.34 vs. 3.97±1.46, p: 0.043). Conclusion: The mean serum testosterone levels were lower in coronary artery disease patients. We failed to document its relation with severity of disease by means of Gensini score. Testosterone administration in patients with lower testosterone levels, but within normal range may be a therapeutic option in coronary artery disease in middle aged men in near future.