One-pot synthesis of magnetic lipid nanoparticles as an efficient sorbent for curcumin determination in magnetic dispersive solid-phase extraction system

Abstract

One-pot synthesis of magnetic lipid nanoparticles (MLNs) was accomplished andaccordingly, applied as a new sorbent for preconcentration and determination of curcumin from aqueous solution, followed by ultraviolet–visible (UV–Vis) spectrophotometry. The MLNs were prepared via microemulsion technique in the presence of oleic acid (OA) as the lipid and Tween 80 as the surfactant. The structure, morphology, and magnetic properties of the MLNs were characterized using FT-IR, XRD, FE-SEM, and VSM. The experimental results revealed that presented MLNs have superparamagnetic property, which results in the easy and quick phase separation and decrease in the extraction time. The influence of operational variables (pH, amount of sorbent, sonication time and type and volume of eluent) were assessed, investigated and finally optimized by the central composite design (CCD). Recoveries between 92.13% and 103.57% in real samples, RSD% <5%, and limits of detection and quantification of 0.022 and 0.073 mg L−1, respectively are good indications of the best performance of the proposed understudy method.