One-step synthesis of CuO nanoparticles based on flame synthesis: As a highly effective non-enzymatic sensor for glucose, hydrogen peroxide and formaldehyde

Abstract

Abstract Non-enzymatic electrochemical sensors for detections of glucose, hydrogen peroxide and formaldehyde, characterized with fast response, convenient operation and high sensitivity, have attracted widespread attention from researchers. In this project, the flame synthesis integrating the merits of simple operation, less-time consumption and low cost was utilized to quickly prepare CuO nanoparticles on carbon cloth (CuO NPs/CC) in one step. The material was then successfully used as a working electrode to achieve the construction of a non-enzymatic electrochemical sensor. In detection of glucose, the results show a low detection limit of 6.8 nM (S/N = 3) and an excellent sensitivity of 12,050 μA mM−1 cm−2, while in hydrogen peroxide detection, the detection limit is 34 nM (S / N = 3), and the sensitivity is 1479 μAmM−1 cm−2. And the detection limit in formaldehyde sensing is 26 nM (S / N = 3), and the sensitivity is 2406 μAmM−1 cm−2. It proves that the flame-synthesized CuO NPs/CC is applicable to the highly sensitive electrocatalysis of glucose, hydrogen peroxide and formaldehyde.