Abstract
We found a very efficient one-pot phosphination reaction starting with Ph 3P, which by reaction with Na metal in liquid ammonia gives Ph 2P − ions that reacted with R 3SnCl to afford (trialkylstannyl)diphenylphosphine. The palladium-catalyzed coupling reaction of these stannanes with aryl iodides yield functionalized phosphines in high yield (69–97%). The use of Ph 3P as starting reagent, the endurance of the reaction to a wide variety of functional groups and the easiness of a one-pot reaction make this method a useful and versatile approach to tertiary phosphine oxides.
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