Abstract
Oncolytic viruses are a type of virus that infects and kills tumor cells more than other cells. They act as “immune modification platforms” that express immune checkpoint inhibitors, tumor antigens, cytokines, and T cell engagers. They can be engineered or tested to selectively multiply and kill cancer cells. Targeting strategies include deleting the gene for the virulence factor and using abnormal signaling pathways in cancer cells to stop them from multiplying and becoming lethal.
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