Abstract
In this review article we will highlight the evidences that how oncogenes are formed due to the physical genetic variations in proto-oncogenes and tumor suppressor genes and various planned immunotherapies which will include- The immune checkpoint inhibitor-opposing antibodies, adoptive cell treatments, and biologic modifiers (cytokines and vaccines). We will make an effort to provide guidance and potential fixes for these issues, along with pertinent sources for foundational research. For suitable studies, a literature search was undertaken from various database sources such as PubMed, EMBASE, and Google Scholar. One type of gene known as an oncogene-a cellular gene that becomes dysfunctional owing to mutation and overexpression-is the cause of cancer. Certain oncogenes seem to inhibit the homeostatic mechanism by limiting the single cell lineage of leukemia stem cells. According to the clonal theory of oncogenes, tumors are thought to begin in a single cell, Moreover, the growth of tumors is closely linked to the prevention of apoptosis, or programmed cell death. These activities of oncogene can be minimized by some immunological therapies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
