Abstract

We describe a universal system for research in combined real-time optoacoustic (OA) and laser-ultrasonic (LU) imaging. The results of its testing on the task of needle insertion into the blood vessel model diagnostics are presented. In OA mode, where laser light is absorbed directly in the sample, the contents of blood vessel model is clearly visible. In LU mode, where the short ultrasonic probe pulse scattered on the sample is detected, the needle is clearly visible. The developed solution combining OA and LU imaging modalities due to the common detection system allowed real-time diagnostics of the position of medical needles (0.63mm and 0.7mm in diameter) inside blood vessel models (1.6mm and 2.4mm in diameter). Frame rate was 10Hz. High longitudinal spatial resolution of the system − 0.1mm − allows distinguishing the two walls of the vessel model and the position of the needle inside.

Highlights

  • Procedures involving needle insertion into biological tissues [1], blood vessels in particular [2], are widespread in medical treatments

  • It is recommended that needle placement should be performed under real-time ultrasound guidance if patients have difficult peripheral venous access [2]

  • OA and LU images can be combined accurately because these modalities share a common receiving system and both images are reconstructed in the same coordinate system. These results suggest that the combined of optoacoustic and laser ultrasonic imaging system may allow reliable determination of the position of the needle in the blood vessel

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Summary

Introduction

Procedures involving needle insertion into biological tissues [1], blood vessels in particular [2], are widespread in medical treatments These procedures are associated with a number of difficulties: blood vessels can be deep and/or poorly palpable, needle can miss or pierce through the selected vessel causing unnecessary damage and side effects which have to be treated later. The possibility of using traditional 3D ultrasound [1,3], optoacoustic tomography [4] and combined optoacoustic & ultrasound imaging [5,6,7] for real-time monitoring of needle/catheter insertion into biological objects has been studied earlier. Short duration of ultrasonic pulses enables high spatial resolution, which can be considerably higher than that of conventional ultrasound imaging Both optoacoustic and laser ultrasonic methods use analogous detector arrays for registration of ultrasonic fields. That is why any experimental research in this area and the development of multi-functional experimental setups are of great importance with a view to developing theoretical models and engineering reliable combined OA and LU imaging systems

Materials and methods
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Conclusions

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