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Old Dog, New Trick: A Tumor-Intrinsic Role for PD-1 in Chemoresistant Tumor Subclones
Publication Date Dec 6, 2022
Abstract
Summary Programmed cell death protein 1 (PD-1) is a well-known driver of immunosuppression and lymphocyte-associated disease progression. Increasing evidence suggests a tumor-intrinsic role for PD-1 in promoting chemoresistance via stem-like features. Moving forward, a recent study implies a novel antitumor mechanism for PD-1 inhibition. See related article by Rotolo et al., p. xxx
Concepts
Stem-like Features Related Article Immunosuppression Disease Mechanism For Inhibition Well-known Driver Tumor Subclones Chemoresistant Tumor PD-1 Inhibition Antitumor Mechanism Cell Death
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Round-ups are the summaries of handpicked papers around trending topics published every week. These would enable you to scan through a collection of papers and decide if the paper is relevant to you before actually investing time into reading it.
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