Abstract
Fibromyxoma is an unusual collagenized variant from odontogenic myxoma neoplasm, presenting a recurrence index of 9.52%. The case report aims to describe an uncommon lesion which presents diagnostic challenges due its similarity to other lesions such as intraosseous neurofibroma and central odontogenic fibroma. An 18-year-old female patient presented a radiolucent lesion discovered on the routine panoramic radiography, which was well circumscribed and had unilocular aspect. Clinically, the patient did not report any symptoms. Then excisional biopsy was performed for histologic evaluation of the lesion, which was observed cells with fusiform or rounded pattern in an abundant fibrous dense stroma and sometimes myxoid. Immunohistochemical analysis were request and the results were S-100(-), CK19(-), SMA(-), and vimentin (+); consequently the diagnosis of odontogenic fibromyxoma was confirmed by morphologic and immunohistochemical findings. Finally, the treatment of choice was enucleation associated with curettage due to good prognosis and she is under follow-up.
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