Abstract
AbstractAntibiotics received by sewage treatment plants may be the causative factor in spreading antibiotic resistance bacteria in the aquatic environment. The current study investigates the distribution of antimicrobial-resistant Escherichia coli (E. coli) in four sewage treatment plants (STPs) in South India receiving hospital and domestic wastewater in different proportions. A total of 221 E. coli isolates were checked for antimicrobial resistance against 16 antimicrobials. Among the antimicrobials tested, ampicillin (AMP) and cefazolin (CFZ) showed resistance between 20% and 90%, nalidixic acid (NAL) and ciprofloxacin (CIP) showed resistance between 15% and 75% and chloramphenicol (CHL) showed resistance between 2% and 20%. Based on the observations, there is no significant difference between the wastewater inlet and outlet, suggesting that treatment process was not effective in reducing the resistance. In conclusion, the trends of antimicrobial resistance pattern show that the levels of resistance were slightly higher in hospital wastewater than domestic wastewater.This article has been made Open Access thanks to the generous support of a global network of libraries as part of the Knowledge Unlatched Select initiative.
Highlights
Masato Akiba Division of Bacterial and Parasitic Disease, National Institute of Animal Health, National Agriculture and Food ResearchOrganization, 3-1-5 Kannondai, Tsukuba, Ibaraki, 305-0856, JapanKeerthi Siri Guruge Pathology and Pathophysiology Research Division, Organization, Kannondai 3-1-5, Tsukuba 305-0856, JapanKalwaje Eshwara Vandana Department of Microbiology, Kasturba MedicalCollege, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaVirendra Kumar Radiation Technology Development Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, IndiaThis article has been made Open Access thanks to the generous support of a global network of libraries as part of the Knowledge Unlatched Select initiative.Antimicrobial resistance has become a significant threat to public health, as antibiotics commonly used to treat infections are often becoming ineffective
The prevalence of antimicrobial resistance of E. coli was tested against 16 antimicrobials
The highest prevalence of resistance was recorded in sewage treatment plants (STPs) 1, STP 2 and STP 4, respectively, for AMP, CFZ, CTX, FEP, TET, nalidixic acid (NAL), SUL and CIP antimicrobials
Summary
Keerthi Siri Guruge Pathology and Pathophysiology Research Division, Organization, Kannondai 3-1-5, Tsukuba 305-0856, Japan. Antimicrobial resistance has become a significant threat to public health, as antibiotics commonly used to treat infections are often becoming ineffective. Praveenkumarreddy et al | Occurrence of antimicrobial-resistant E. coli in STPs of South India Journal of Water, Sanitation and Hygiene for Development | 10.1 | 2020 drugs in animal and human health is an emerging concern (Prabhasankar et al ). Escherichia coli (E. coli) is considered a dominant microorganism in understanding the contamination by antimicrobial-resistant bacteria originating from human and animal faeces. The bacterial communities which include E. coli have been associated with the antibiotic resistance genes that can be transferred to human and animal flora, where they can exert intense pressure for the spread of resistance (Adefisoye & Okoh )
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