Abstract

Autophagy is a process by which the cytoplasm of the cell segregates and degrades endogenous macromolecules and organelles. Autophagy plays an important role in the degradation of intracellular components during physiological cell functioning. This paper describes the morphology of bird hepatocytes with reference to abundant formation of autophagosomes.Six house sparrows were purchased from a local dealer, and, on examination, all were apparently healthy, did not show any sign of starvation or disease. Their liver was removed after cervical dislocation and was doubly fixed with glutaraldehyde-osmium, and processed with conventional methods.The hepatocytes were generally polyhedral, sometimes slightly oval. The nuclei were round, slightly eccentric and contained one or two prominent nucleoli. Nuclear chromatin exhibited the normal structure and organization of hetero- and euchromatin. The cytoplasm showed abundant mitochondria round and elliptic. No intramitochondrial vacuolization and swelling were seen and cristae exhibited the normal structure described for liver cells. The Golgi apparatus was poorly developed.

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