Abstract
A 44-year-old construction designer developed acute dermatitis on his palms, dorsal side of hands, face and neck. According to the patient, the lesions were caused by the occupational daily contact with diazo copy paper. It contained thiourea and dimethylthiourea as antioxidants. Patch tests proved sensitization to diazo copy paper—exposed and unexposed—thiourea, dimethylthiourea, and to the ammonia salts used as developers. Thioureas reactions were intensified after the standard irradiation for photo-patch testing. Considering that thioureas and derivatives are used in almost all kinds of diazo photocopy paper, the authors believe that thiourea allergy from this source has virtually been overlooked.
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