Abstract
Objective: The aim of this study was to evaluate obstetric and neonatal outcomes of pregnancies with mild gestational hyperglycemia diagnosed at gestational diabetes mellitus screening.Study design: Between September 2016 and August 2017, the pregnant women diagnosed as normal glycaemia or mild gestational hyperglycemia according to the results of gestational diabetes mellitus screening with 50 g oral glucose challenge test, and 100 g oral glucose tolerance test were compared [Normal glycaemia: Blood glucose value <140 mg/dL 1 hour after 50 g oral glucose challenge test].Results: The following results were obtained in the normal glycaemia and mild gestational hyperglycemia groups respectively: Mean gestational age at birth, 38.9±1.6 and 39±1.9 weeks; preterm, term, post-term birth rates, 6%, 86.2% 7.8% and 6.8%, 86.4% and 6.8%; cesarean delivery rate, 30.9% and 34.9%; birth weight 3227.9±394.9 and 3241.05±418.5 g; small for gestational age, 4.4% and 2.3%; large for gestational age 4.6% and 7%; without any significant difference between the groups. Five minute APGAR scores were significantly lower in the mild gestational hyperglycemia group compared to the normal glycaemia group.Conclusion: There was no significant increase in adverse pregnancy outcomes such as preterm birth, post-term birth, increased caesarean delivery rate, small for gestational age and large for gestational age, except for a significant decrease in 5 minute APGAR scores in the mild gestational hyperglycemia group compared to the normal glycaemia group in our study.
Highlights
There was no significant increase in adverse pregnancy outcomes such as preterm birth, post-term birth, increased caesarean delivery rate, small for gestational age and large for gestational age, except for a significant decrease in 5 minute Apgar scores in the mild gestational hyperglycemia group compared to the normal glycaemia group in our study
The American College of Obstetricians and Gynecologist recommends Gestational diabetes mellitus (GDM) screening with a 50 g oral glucose challenge test (OGCT) in all pregnant patients between 24-28th gestational weeks [4,5]
GDM is diagnosed when blood glucose value is ≥200 mg/dL 1 hour after 50 g OGCT or when two or more abnormal glucose values are observed at 100 g oral glucose tolerance test which is the second step of the GDM screening program [6]
Summary
Obstetric and Neonatal Outcomes of Pregnancies with Mild Gestational Hyperglycemia Diagnosed at Gestational Diabetes Mellitus Screening. Adverse pregnancy outcomes in GDM are associated with maternal hyperglycemia [3]. For this reason, it is important to prevent the development of complications by establishing early diagnosis and controlling the maternal hyperglycemia. The American College of Obstetricians and Gynecologist recommends GDM screening with a 50 g oral glucose challenge test (OGCT) in all pregnant patients between 24-28th gestational weeks [4,5]. GDM is diagnosed when blood glucose value is ≥200 mg/dL 1 hour after 50 g OGCT or when two or more abnormal glucose values are observed at 100 g oral glucose tolerance test which is the second step of the GDM screening program [6]. Several recently conducted studies showed an increase in adverse pregnancy outcomes in MGH [7,8,9]
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