O24 Functionality of selected seaweed extracts on selected pharmaceutical applications

Abstract

Cosmetic and pharmaceutical industry is looking more and more for natural marine compounds with key identified bioactivities. The Laboratoires Gilbert are a major French industrial player developing natural origin products in cosmetic and pharmacy markets. ALGAIA is a French company providing R&D services and natural extracts from macro- and micro-algae. The present study is based on a private close collaboration between the Laboratoires Gilbert and ALGAIA. The main approach has been to extract, characterise and test bioactivities of novel seaweed extracts towards cosmetic and pharmaceutical applications. In the overall work, 1 green species, 2 red species and 3 brown seaweed species have been used as starting material for creating more than 50 different extracts. After characterization, these extracts have been screened for different bioactivities, each one implemented with different techniques. In the present work, some of the outcomes related to the brown seaweed species studied will be presented and discussed. The focus will be made between the main composition of the selected extracts including polysaccharides and phenolic compounds and their anti-inflammatory and wound healing activities in particular. The composition between the three species is by nature different but also the compounds extracted vary also by their yields and size, depending on the extraction process used. As a consequence, in our study, the results on each bioactivity tested show different levels and scope of action dependent upon the extract that has been tested. Those results will be presented and discussed in order to propose hypotheses of actions and constitute a strong base for sustainable development of innovative pharmaceutical products based on active seaweed extracts.