Abstract
Cluster headache (CH) is a severe form of primary headache, characterized by trigeminal-autonomic system activation. Bouts, lasting 15-180 minutes, occur 1-8 times a day, for a period persisting for weeks or months, followed by a full remission. However, about 10-15% of patients have no remission periods and their CH is defined chronic (CCH). While symptomatic treatment is often effective, preventive treatments are limited. Our group has already reported the case of a patient affected by refractory CCH who underwent a complete and sustained response to rotigotine, a non-ergoline D3-like receptor agonist, also with a 5HT1A effect, administrated by transdermal patches. Here we report a case series of patients that have tried transdermal rotigotine for their drug-resistant CH.
Highlights
Cluster headache (CH) is a severe form of primary headache, characterized by trigeminal-autonomic system activation
Our group has already reported the case of a patient affected by refractory CH is defined chronic (CCH) who underwent a complete and sustained response to rotigotine, a non-ergoline D3-like receptor agonist, with a 5HT1A effect, administrated by transdermal patches
Out of 11 CCH patients, 8 were considered responders since CH disappeared (5 cases) or significantly decreased
Summary
Cluster headache (CH) is a severe form of primary headache, characterized by trigeminal-autonomic system activation. Rotigotine improves drug-resistant cluster headache: a case series From Abstracts from the 1st Joint ANIRCEF-SISC Congress Rome, Italy.
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