Abstract
Nucleic acids not only store genetic information in their primary sequence but also exhibit biological functions through the formation of their unique structures [...]
Highlights
Based on such functions and specific and designable complementary recognition through base pairing, nucleic acids are considered attractive molecules as functional units for biotechnological applications
Life in biological systems is maintained by the cooperative actions of various biomolecules, such as nucleic acids, proteins, lipids, and small organic molecules
With the development of chemical and biological technologies related to nucleic acids, the details of the mechanisms of such cooperative actions between nucleic acids and other biomolecules have been elucidated
Summary
Based on such functions and specific and designable complementary recognition through base pairing, nucleic acids are considered attractive molecules as functional units for biotechnological applications. In addition to the complementary sequence, nucleic acids form complex tertiary structures that recognize other biomolecules such as proteins and small molecule metabolites. Nucleic acids with potential to recognize another molecule, have been applied as functional units in biosensors.
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